Autoimmune hemolytic anemia: From lab to bedside

Autoimmune Hemolytic Anemia

Autoimmune Hemolytic Anemia due to Varicella Infection

Varicella is usually benign exanthematous disease, which primarily affects children. The common complications are bacterial infection of skin eruptions, pneumonia, cerebellar ataxia, hepatitis, thrombocytopenia and arthritis [1]. Autoimmune hemolytic anemia (AIHA) is a rare complication of varicella and only few cases are reported [2-5]. Overall the incidence of AIHA in children is as low as 0....

Thymoma with Autoimmune Hemolytic Anemia

A 38-year-old Japanese male was referred to our hospital with abnormal chest X-ray results and severe Coombs-positive hemolytic anemia. He was diagnosed with a stage IV, WHO type A thymoma and was treated with oral prednisolone (1 mg/kg/day) and subsequent chemotherapy. After chemotherapy, the patient underwent surgical resection of the thymoma. Hemolysis rapidly disappeared and did not return ...

Immunotherapy-associated autoimmune hemolytic anemia

BACKGROUND Immunotherapy has been widely used in the treatment of several solid and hematologic malignancies. Checkpoint inhibitors have been the forefront of cancer immunotherapy in recent years. Cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death 1 (PD-1) pathway are the prototypic checkpoint targets for immunotherapy. When combined, CTLA-4 and PD-1 checkpoint inhib...

Reticulocytopenia in autoimmune hemolytic anemia.

ETICULOCYTOSIS is gemserally regarded as a characteristic feature of the hensolytic symsdrome. The outpouring of young red cells is ouse of the bone marrow’s reactiomss to the challenge of aisemia, atsd the numssber of reticulocytes it produces is oftets a good measure of the severity of the hemolytic process. Whets the red cell life spams is very short mssost of the cells ims the circulation n...